The idea of having my genome sequenced kind of freaks me out. I’m certainly warming to it, but I don’t like the idea of finding out about a deep, dark family secret or the fact that I’m predisposed to some kind of cancer from a DNA test. I know it’s irrational, and I know that I’ll overcome it eventually. I fully expect that within 20 years every child born in the U.S. will have his or her genome sequenced at birth. So maybe I should just the bite the bullet and get my genome sequenced. But if I’m going to do that, I need your help. The other day I came across a post about Palo Alto, CA based DNAnexus on Hacker News (an awesome site for programmers and people interested in startups). The post was focused on the company’s referral program that offers $20,000 and a full genome sequencing to anyone who refers a software engineer that they hire. That clearly caught my attention (I am trying to run a business here), but, more importantly, it introduced me to what DNAnexus is doing. A single genome contains over 100 gigabytes of data. Storing and analyzing this data requires some serious hardware, especially if you want to do it on a large scale. DNAnexus is an “early-stage software technology company that aims to become the data platform of the genome era.”

You Are the Data

It’s mind blowing when you think about how much data is contained in every single cell of your body. When you multiply that out by the number of people in the world, you realize that computing is going to have to come a long way to be able to be able to crunch all of that data. DNAnexus wants to be the leader by “building the DNA operating system – a platform that will handle the data deluge coming from exponentially increasing whole human genome sequencing.” It’s hard to say what kind of things will be made possible as whole human genome sequencing becomes more common, but you can bet that it will lead to some amazing medical breakthroughs (see their testimonials here). For DNAnexus though, it’s really all about hardware and software breakthroughs. They have built their “infrastructure from the ground up to run on Amazon Web Services, the world’s leading cloud computing provider,” so that they can deliver “computing and storage infrastructure” with 100,000s of CPUs and 100s of petabytes of storage available.

If you’re interested in the intersection of computing technology and genetics, you have to take a look at jobs at DNAnexus. I’m not only saying that because they offer an amazing referral bonus; I really think that they’re doing something that has amazing potential for impact on the human race. DNAnexus is looking to hire Systems Engineers, Security Engineers, Web Services Engineers, Data Visualization and Interaction Engineers, UI/UX Engineers, and Computational Genomics, Algorithms, and Machine Learning Engineer. You can apply for any of these positions on your own if you’d like, but if you want to help support One Day, One Job (and help me overcome my fear of having my genome sequenced) then send me an e-mail to willy@onedayonejob.com with your résumé or LinkedIn profile and I’ll submit it according to the rules of the referral promotion.

Links to Help You Begin Your Research

• DNAnexus.com
• Jobs at DNAnexus
• About DNAnexus
• Leadership at DNAnexus
• DNAnexus Testimonials
• DNAnexus News
• DNAnexus’ Blog

Would you get your genome sequenced?

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